Structure of PDB 6yuf Chain A Binding Site BS01

Receptor Information
>6yuf Chain A (length=384) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRLLRLEVENFKSYRGHQIIGPFEDFTSIIGPNGAGKSNLMDAISFVLGV
KSSHLRSTNVKELIPTTAYVKLMYELDNGEQREYKRAITPSGATEYKIDE
EIVTFSEYCGSLQKENILVRARNFLVFQGDVETIASQSPLELSKLVEQIS
GSLEYKSEYDKSKDEQDKAVNLSAHSFNKKRGINAELRLETVETRLAKLD
EEFAAARKAAKNAKERFNAVKQKRLQKFQAAFSHISEQIDPIYKELTKSP
AFPLGGTAYLTLDDLDEPYLGGIKFHAMPPMKRFRDMDQLSGGEKTMAAL
ALLFAIHSYQPSPFFVLDEIDAALDQTNVTKIANYIRQHASSGFQFVVIS
LKNQLFSKSEALVGIYRDQQENSSRTLSINLEGY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6yuf A Structure-Based Mechanism for DNA Entry into the Cohesin Ring.
Resolution3.94 Å
Binding residue
(original residue number in PDB)		T123 F124
Binding residue
(residue number reindexed from 1)		T104 F105
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0061776 topological DNA co-entrapment activity
Biological Process
GO:0007062 sister chromatid cohesion
GO:0007064 mitotic sister chromatid cohesion
GO:0051276 chromosome organization
GO:0051301 cell division
GO:0140588 chromatin looping
Cellular Component
GO:0000779 condensed chromosome, centromeric region
GO:0005634 nucleus
GO:0005694 chromosome
GO:0008278 cohesin complex
GO:0030892 mitotic cohesin complex
GO:0030893 meiotic cohesin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6yuf, PDBe:6yuf, PDBj:6yuf
PDBsum6yuf
PubMed32755595
UniProtO94383|SMC1_SCHPO Structural maintenance of chromosomes protein 1 (Gene Name=psm1)

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