Structure of PDB 6yu8 Chain A Binding Site BS01

Receptor Information
>6yu8 Chain A (length=268) Species: 128948 (Sudan virus - Boniface, Sudan,1976) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRLVVPFFKIEPSPEESRSNIKGLLQHLRTMVSSMHYKLDEVLWEYNKF
ESAVTLAEGEGSGALLLIQKYGVKKLFLNTLATEHSIESEVISGYTTPRM
LLPIMPKTHRGELEVILNNSASQITDITHRDWFSNQKNRIPNDADIITMD
AETTENLDRSRLYEAVYTIICNHINPKTLKVVILKVFLSDLDGMCWINNY
LAPMFGSGYLIKPITSSAKSSEWYLCLSNLLSTLRTTQHQTQANCLHVVQ
CALQQQVQRGSYWLHHLT
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6yu8 Chain A Residue 2114 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6yu8 First insights into the structural features of Ebola virus methyltransferase activities.
Resolution1.841 Å
Binding residue
(original residue number in PDB)		H1811 E1832 D1924
Binding residue
(residue number reindexed from 1)		H37 E58 D150
Annotation score1
Enzymatic activity
Enzyme Commision number 2.1.1.375: NNS virus cap methyltransferase.
2.7.7.48: RNA-directed RNA polymerase.
2.7.7.88: GDP polyribonucleotidyltransferase.
3.6.1.-
External links
PDB RCSB:6yu8, PDBe:6yu8, PDBj:6yu8
PDBsum6yu8
PubMed33503246
UniProtQ5XX01|L_EBOSU RNA-directed RNA polymerase L (Gene Name=L)

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