Structure of PDB 6y43 Chain A Binding Site BS01

Receptor Information
>6y43 Chain A (length=222) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMTKPVGPWQDCAEARQAGHEQSGVYELRVGRHVVSVWCEQQLEGGGWTV
IQRRQDGSVNFFTTWQHYKAGFGRPDGEYWLGLEPVYQLTSRGDHELLVL
LEDWGGRGARAHYDGFSLEPESDHYRLRLGQYHGDAGDSLSWHNDKPFST
VDRDRDSYSGNCALYQRGGWWYHACAHSNLNGVWHHGGHYRSRYQDGVYW
AEFRGGAYSLRKAAMLIRPLKL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6y43 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6y43 Fibrinogen-like globe domain of human ANGPTL6
Resolution1.6 Å
Binding residue
(original residue number in PDB)
D402 D404 Y406 G408
Binding residue
(residue number reindexed from 1)
D154 D156 Y158 G160
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6y43, PDBe:6y43, PDBj:6y43
PDBsum6y43
PubMed
UniProtQ8NI99|ANGL6_HUMAN Angiopoietin-related protein 6 (Gene Name=ANGPTL6)

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