Structure of PDB 6xxr Chain A Binding Site BS01

Receptor Information
>6xxr Chain A (length=112) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVV
GRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANV
FASAMMHALEVL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6xxr Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Resolution1.48 Å
Binding residue
(original residue number in PDB)		M14 Y16 W23 K69 N71 F77 Q79 R81 V86
Binding residue
(residue number reindexed from 1)		M15 Y17 W24 K70 N72 F78 Q80 R82 V87
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6xxr, PDBe:6xxr, PDBj:6xxr
PDBsum6xxr
PubMed33184177
UniProtQ8N8S7|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)

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