Structure of PDB 6x4s Chain A Binding Site BS01

Receptor Information
>6x4s Chain A (length=152) Species: 7070 (Tribolium castaneum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DVKTLVNQLYEALNVREHQLQKEVELTTQLETLQQELLPLEEKKLELEQV
ANRRSNWMAWAGLGLMSVQFGILARLTWWEYSWDIMEPVTYFVTYGTAMA
AYAYFVLTRVRDRQQLLLLHKKAKKTGFDVNQYNVLKDQIAKLELDLKRL
RD
Ligand information
>6x4s Chain E (length=25) Species: 7070 (Tribolium castaneum) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
IRLILTVVPGLLIGAAISKNIANFL
Receptor-Ligand Complex Structure
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PDB6x4s Structure and Reconstitution of an MCU-EMRE Mitochondrial Ca 2+ Uniporter Complex.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
S244 R252 E257
Binding residue
(residue number reindexed from 1)
S67 R75 E80
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0036444 calcium import into the mitochondrion
GO:0051560 mitochondrial calcium ion homeostasis
Cellular Component
GO:1990246 uniplex complex

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Biological Process

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Cellular Component
External links
PDB RCSB:6x4s, PDBe:6x4s, PDBj:6x4s
PDBsum6x4s
PubMed32841658
UniProtD6WIX5|MCU_TRICA Calcium uniporter protein, mitochondrial (Gene Name=MCU);
D6X268

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