Structure of PDB 6x39 Chain A Binding Site BS01

Receptor Information
>6x39 Chain A (length=100) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGSGPPRKVEVEPLNSTAVHVSWKLPVPHGQIRGYQVTYVRLENGEPRGQ
PIIQDVMLAEAQETTISGLTPETTYSITVAAYTTKGDGARSKPKVVTTTG
Ligand information
Ligand IDSOR
InChIInChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1
InChIKeyFBPFZTCFMRRESA-JGWLITMVSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C([C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)O
CACTVS 3.341OC[CH](O)[CH](O)[CH](O)[CH](O)CO
ACDLabs 10.04OC(C(O)CO)C(O)C(O)CO
CACTVS 3.341OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
OpenEye OEToolkits 1.5.0C(C(C(C(C(CO)O)O)O)O)O
FormulaC6 H14 O6
Namesorbitol;
D-sorbitol;
D-glucitol
ChEMBLCHEMBL1682
DrugBankDB01638
ZINCZINC000018279893
PDB chain6x39 Chain A Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6x39 Complex protein interactions mediate Drosophila Lar function in muscle tissue.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		R750 L751 E752 T783
Binding residue
(residue number reindexed from 1)		R41 L42 E43 T74
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
External links
PDB RCSB:6x39, PDBe:6x39, PDBj:6x39
PDBsum6x39
PubMed35622884
UniProtA2A8L5|PTPRF_MOUSE Receptor-type tyrosine-protein phosphatase F (Gene Name=Ptprf)

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