Structure of PDB 6wz9 Chain A Binding Site BS01

Receptor Information
>6wz9 Chain A (length=95) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSA
VMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>6wz9 Chain I (length=148) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cacaggatgtatatatctgacacgtgcctggagactagggagtaatcccc
ttggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgct
agagctgtctacgaccaattgagcggcctcggcaccgggattctccag
Receptor-Ligand Complex Structure
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PDB6wz9 Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Y41 R42 T45 R72 R83 F84 R116 V117 T118 M120
Binding residue
(residue number reindexed from 1)		Y3 R4 T7 R34 R45 F46 R78 V79 T80 M82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6wz9, PDBe:6wz9, PDBj:6wz9
PDBsum6wz9
PubMed32939087
UniProtP84233|H32_XENLA Histone H3.2

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