Structure of PDB 6wyb Chain A Binding Site BS01

Receptor Information
>6wyb Chain A (length=739) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MILDTDYITEDGKPVIRIFKKENGEFKIEYDRTFEPYLYALLKDDSAIEE
VKKITAERHGTVVTVKRVEKVQKKFLGRPVEVWKLYFTHPQDVPAIMDKI
REHPAVIDIYEYDIPFAIRYLIDKGLVPMEGDEELKLLAFDIETLYEFAE
GPILMISYADEEGARVITWDLPYVDVVSTEREMIKRFLRVVKEKDPDVLI
TYDGDNFDFAYLKKRCEKLGINFALGRDGSEPKIQRMGDRFAVEVKGRIH
FDLYPVIRRTINLPTYTLEAVYEAVFGQPKEKVYAEEITTAWETGENLER
VARYSMEDAKVTYELGKEFLPMEAQLSRLIGQSLWDVSRSSTGNLVEWFL
LRKAYERNELAPNKPDEKELARRHQSHEGGYIKEPERGLWENIVYLDFRS
LYPSIIITHNVSPDTLNREGCKEYDVAPQVGHRFCKDFPGFIPSLLGDLL
EERQKIKKRMKATIDPIERKLLDYRQRAIKILANSLYGYYGYARARWYCK
ECAESVIAWGREYLTMTIKEIEEKYGFKVIYSDTDGFFATIPGADAETVK
KKAMEFLKYINAKLPGALELEYEGFYKRGLFVTKKKYAVIDEEGKITTRG
LEIVRRDWSEIAKETQARVLEALLKDGDVEKAVRIVKEVTEKLSKYEVPP
IHKQITRDLKDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIV
DRAIPFDEKYDAEYYIEKQVLPAVERILRAFGYRKEDLR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6wyb How a B family DNA polymerase has been evolved to copy RNA.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H384 T590 K592 K593 R709 I710
Binding residue
(residue number reindexed from 1)		H377 T583 K585 K586 R698 I699
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0071897 DNA biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6wyb, PDBe:6wyb, PDBj:6wyb
PDBsum6wyb
PubMed32817521
UniProtD0VWU9

[Back to BioLiP]