Structure of PDB 6wvf Chain A Binding Site BS01

Receptor Information
>6wvf Chain A (length=386) Species: 6100,83333 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KGEELFTGVVPILVELDGDVNGHKFSVRGEGEGDATNGKLTLKFICTTGK
LPVPWPTLVTTLVQCFSRYPDHMKRHDFFKSAMPEGYVQERTISFKDDGT
YKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNNQASQGRGAWL
LMAFTALALELTALWFQHVMLLKPCVLCIYERVALFGVLGAALIGAIAPK
PLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFATSDFMVRFPEWLPLD
KWVPQVFVASGDCAERQWDFLGLEMPQWLLGIFIAYLIVAVLVVISQPFK
NSHNVYITADKQKNGIKANFKIRHNVEDGSVQLADHYQQNTPIGDGPVLL
PDNHYLSTQSVLSKDPNEKRDHMVLLEFVTAAGITH
Ligand information
Ligand IDUQ1
InChIInChI=1S/C14H18O4/c1-8(2)6-7-10-9(3)11(15)13(17-4)14(18-5)12(10)16/h6H,7H2,1-5H3
InChIKeySOECUQMRSRVZQQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341COC1=C(OC)C(=O)C(=C(C)C1=O)CC=C(C)C
OpenEye OEToolkits 1.5.0CC1=C(C(=O)C(=C(C1=O)OC)OC)CC=C(C)C
ACDLabs 10.04O=C1C(=C(C(=O)C(OC)=C1OC)C)C\C=C(/C)C
FormulaC14 H18 O4
NameUBIQUINONE-1
ChEMBLCHEMBL1236594
DrugBankDB08689
ZINCZINC000001559692
PDB chain6wvf Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6wvf Termini restraining of small membrane proteins enables structure determination at near-atomic resolution.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		L164 A168 P179 C183 E186 R187 L190 L285 F289
Binding residue
(residue number reindexed from 1)		L159 A163 P174 C178 E181 R182 L185 L279 F283
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0009055 electron transfer activity
GO:0015035 protein-disulfide reductase activity
GO:0016491 oxidoreductase activity
GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor
GO:0048039 ubiquinone binding
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0006457 protein folding
GO:0008218 bioluminescence
GO:0009408 response to heat
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6wvf, PDBe:6wvf, PDBj:6wvf
PDBsum6wvf
PubMed33355146
UniProtP0A6M2|DSBB_ECOLI Disulfide bond formation protein B (Gene Name=dsbB);
P42212|GFP_AEQVI Green fluorescent protein (Gene Name=GFP)

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