Structure of PDB 6wud Chain A Binding Site BS01

Receptor Information
>6wud Chain A (length=183) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QTVFTHEQLEAYQDCTFFTRKEIMRLFYRYQDLAPQLVPLDYTTCPDVKV
PYELIGSMPELKDNPFRQRIAQVFSEDGDGHMTLDNFLDMFSVMSEMAPR
DLKAYYAFKIYDFNNDDYICAWDLEQTVTKLTRGELSAEEVSLVCEKVLD
EADGDHDGRLSLEDFQNMILRAPDFLSTFHIRI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6wud Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6wud CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.
Resolution1.84 Å
Binding residue
(original residue number in PDB)		D116 N118 D120 Y122 D127
Binding residue
(residue number reindexed from 1)		D112 N114 D116 Y118 D123
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0055074 calcium ion homeostasis

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Molecular Function
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Biological Process
External links
PDB RCSB:6wud, PDBe:6wud, PDBj:6wud
PDBsum6wud
PubMed34089643
UniProtQ96Q77|CIB3_HUMAN Calcium and integrin-binding family member 3 (Gene Name=CIB3)

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