Structure of PDB 6wo2 Chain A Binding Site BS01
Receptor Information
>6wo2 Chain A (length=101) Species:
9606
(Homo sapiens) [
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EMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGN
DVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
V
Ligand information
>6wo2 Chain C (length=3) Species:
32630
(synthetic construct) [
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YKN
Receptor-Ligand Complex Structure
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PDB
6wo2
Some thermodynamic effects of varying nonpolar surfaces in protein-ligand interactions.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
R67 R86 S88 S90 S96 Q106 H107 F108 K109 L120 W121
Binding residue
(residue number reindexed from 1)
R14 R33 S35 S37 S43 Q53 H54 F55 K56 L67 W68
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6wo2
,
PDBe:6wo2
,
PDBj:6wo2
PDBsum
6wo2
PubMed
32916312
UniProt
P62993
|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)
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