Structure of PDB 6wku Chain A Binding Site BS01

Receptor Information
>6wku Chain A (length=677) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTRGFVFTRHSQTTAIPSCPEGTVPLYSGFSFLFVQGNQRAHGQDLGTLG
SCLQRFTTMPFLFCNVNDVCNFASRNDYSYWLSTPALMPMNMAPITGRAL
EPYISRCTVCEGPAIAIAVHSQTTDIPPCPHGWISLWKGFSFIMFTSAGS
EGTGQALASPGSCLEEFRASPFLECHGRGTCNYYSNSYSFWLASLNPERM
FRKPIPSTVKAGELEKIISRCQVCMGTGFLLVLHSQTDQEPTCPLGMPRL
WTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQRN
DRSYWLASAAPLPMMPLSEEAIRPYVSRCAVCEAPAQAVAVHSQDQSIPP
CPQTWRSLWIGYSFLMHTGAGDQGGGQALMSPGSCLEDFRAAPFLECQGR
QGTCHFFANKYSFWLTTVKADLQFSSAPAPDTLKESQAQRQKISRCQVCV
APGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHGQDLGTAGS
CLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSIQ
PFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAE
GSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMF
SKPQSETLKAGDLRTRISRCQVCMKRT
Ligand information
Ligand IDCL
InChIInChI=1S/ClH/h1H/p-1
InChIKeyVEXZGXHMUGYJMC-UHFFFAOYSA-M
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cl-]
FormulaCl
NameCHLORIDE ION
ChEMBL
DrugBankDB14547
ZINC
PDB chain6wku Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6wku Collagen IV alpha 345 dysfunction in glomerular basement membrane diseases. II. Crystal structure of the alpha 345 hexamer.
Resolution1.76 Å
Binding residue
(original residue number in PDB)		A74 R76
Binding residue
(residue number reindexed from 1)		A73 R75
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005201 extracellular matrix structural constituent
Cellular Component
GO:0005581 collagen trimer

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Molecular Function
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Cellular Component
External links
PDB RCSB:6wku, PDBe:6wku, PDBj:6wku
PDBsum6wku
PubMed33775698
UniProtP29400;
P53420;
Q01955

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