Structure of PDB 6wh0 Chain A Binding Site BS01

Receptor Information
>6wh0 Chain A (length=524) Species: 562,6087 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQ
VAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRY
NGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMF
NLQEPYFTWPLIAADGGYAFKYKYDIKDVGVDNAGAKAGLTFLVDLIKNK
HMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKG
QPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAV
ALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAAS
GRQTVDEALKDAQTNSSSPNAQEDNYKRIVKSYVGEKLRKKGLKIRGYEG
EELKPPVIEIAKTLQRVGDELESANTDFFKNMCDQLQITPSTAYPTFQSI
ADEIFVSGKNWGRVVAFLTFGGNFAVHCALRADMGEEYVDRVVNWISKYM
AVNLDYWINQQGGWDGFLIFFEKT
Ligand information
>6wh0 Chain B (length=26) Species: 6087 (Hydra vulgaris) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NGTVNKEVAHCLKRIGDDLVNNHQLN
Receptor-Ligand Complex Structure
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PDB6wh0 The structural basis of Bcl-2 mediated cell death regulation in hydra.
Resolution1.99 Å
Binding residue
(original residue number in PDB)		E56 L57 N61 F64 I86 E89 I90 N96 G98 R99 V101 F106 F156 F157
Binding residue
(residue number reindexed from 1)		E420 L421 N425 F428 I450 E453 I454 N460 G462 R463 V465 F470 F520 F521
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015144 carbohydrate transmembrane transporter activity
GO:1901982 maltose binding
Biological Process
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0034219 carbohydrate transmembrane transport
GO:0042956 maltodextrin transmembrane transport
GO:0042981 regulation of apoptotic process
GO:0055085 transmembrane transport
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6wh0, PDBe:6wh0, PDBj:6wh0
PDBsum6wh0
PubMed32776134
UniProtA7LM80;
C3SHQ8

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