Structure of PDB 6wdt Chain A Binding Site BS01
Receptor Information
>6wdt Chain A (length=296) Species:
42789
(enterovirus D68) [
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IESIIKTATDTVKSEINAELGVVPSLNAVETGATSNTEPEEAIQTRTVIN
QHGVSETLVENFLSRAALVSKRSFEYKDHTSSTARADKNFFKWTINTRSF
VQLRRKLELFTYLRFDAEITILTTVAVNGSGNNTYVGLPDLTLQAMFVPT
GALTPEKQDSFHWQSGSNASVFFKISDPPARITIPFMCINSAYSVFYDGF
AGFEKNGLYGINPADTIGNLCVRIVNEHQPVGFTVTVRVYMKPKHIKAWA
PRPPRTLPYMSIANANYKGKERAPNALSAIIGNRDSVKTMPHNIVN
Ligand information
>6wdt Chain D (length=28) Species:
42789
(enterovirus D68) [
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INFYKDSYAASASKQDFSQDPSKFTEPV
Receptor-Ligand Complex Structure
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PDB
6wdt
Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Resolution
3.1 Å
Binding residue
(original residue number in PDB)
I1 E2 I4 I5 G32 T34 S55 E60 D116 T183 P185 K244 H245
Binding residue
(residue number reindexed from 1)
I1 E2 I4 I5 G32 T34 S55 E60 D116 T183 P185 K244 H245
Enzymatic activity
Enzyme Commision number
2.7.7.48
: RNA-directed RNA polymerase.
3.4.22.28
: picornain 3C.
3.4.22.29
: picornain 2A.
3.6.1.15
: nucleoside-triphosphate phosphatase.
External links
PDB
RCSB:6wdt
,
PDBe:6wdt
,
PDBj:6wdt
PDBsum
6wdt
PubMed
32620559
UniProt
A0A097BW12
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