Structure of PDB 6wcw Chain A Binding Site BS01

Receptor Information
>6wcw Chain A (length=247) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NAQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYF
CQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDIN
SALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFDTVPGHLTED
LHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQN
EDDIIFPFELHKCRTCEECKACYHKACFKSGSCPRCERLQARREALA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6wcw Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6wcw Structural basis for autophagy inhibition by the human Rubicon-Rab7 complex.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		C721 C724 C747 C750
Binding residue
(residue number reindexed from 1)		C25 C28 C51 C54
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6wcw, PDBe:6wcw, PDBj:6wcw
PDBsum6wcw
PubMed32632011
UniProtQ92622|RUBIC_HUMAN Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (Gene Name=RUBCN)

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