Structure of PDB 6way Chain A Binding Site BS01
Receptor Information
>6way Chain A (length=106) Species:
9606
(Homo sapiens) [
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SGREEDPHEGKIWFHGKISKQEAYNLLMTVGQVSSFLVRPSDNTPGDYSL
YFRTNENIQRFKISPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLK
EPVPMQ
Ligand information
>6way Chain V (length=8) Species:
9606
(Homo sapiens) [
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DYAEPMDA
Receptor-Ligand Complex Structure
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PDB
6way
The GTPase-activating protein p120RasGAP has an evolutionarily conserved "FLVR-unique" SH2 domain.
Resolution
1.5 Å
Binding residue
(original residue number in PDB)
S379 N381 S387 R398 F399 K400 M411 G412 Y426 I431 E433
Binding residue
(residue number reindexed from 1)
S41 N43 S49 R60 F61 K62 M73 G74 Y88 I93 E95
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6way
,
PDBe:6way
,
PDBj:6way
PDBsum
6way
PubMed
32540970
UniProt
P20936
|RASA1_HUMAN Ras GTPase-activating protein 1 (Gene Name=RASA1)
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