Structure of PDB 6w7b Chain A Binding Site BS01

Receptor Information
>6w7b Chain A (length=259) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KWKTVSTIFLVVVLYLIIGATVFKALEQPQEISQRTTIVIQREKFLRAHP
CVSDQELDELIQQIVAAINAGIIPLGASSNQVSHWDLGSSFFFAGTVITT
IGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKV
EDKIRIISTIIFILFGCVLFVALPAVIFGWSALDAIYFVVITLTTIGFGD
YVAGGSKPVVWFWILVGLAYFAAVLSMIGDWLRVIAKKTKEAVGEFRAHA
AEWTANVTS
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain6w7b Chain A Residue 406 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6w7b K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Resolution3.88 Å
Binding residue
(original residue number in PDB)		T142 I143 G144 T251 I252 G253
Binding residue
(residue number reindexed from 1)		T100 I101 G102 T195 I196 G197
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w7b, PDBe:6w7b, PDBj:6w7b
PDBsum6w7b
PubMed33127683
UniProtP97438|KCNK2_MOUSE Potassium channel subfamily K member 2 (Gene Name=Kcnk2)

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