Structure of PDB 6w51 Chain A Binding Site BS01
Receptor Information
>6w51 Chain A (length=268) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTTELVETRPAGDGTFQKWAAVVVPSG
QEQRYTCHVQHEGLPKPL
Ligand information
>6w51 Chain C (length=9) Species:
9606
(Homo sapiens) [
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HMTEVVRHC
Receptor-Ligand Complex Structure
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PDB
6w51
Targeting a neoantigen derived from a common TP53 mutation.
Resolution
3.53 Å
Binding residue
(original residue number in PDB)
Y7 F9 M45 E63 R65 K66 V67 D77 T80 Y99 Y116 T143 W147 A150 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 F9 M45 E63 R65 K66 V67 D77 T80 Y99 Y116 T143 W147 A150 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6w51
,
PDBe:6w51
,
PDBj:6w51
PDBsum
6w51
PubMed
33649166
UniProt
A0A140T913
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