Structure of PDB 6w1k Chain A Binding Site BS01

Receptor Information
>6w1k Chain A (length=312) Species: 4530 (Oryza sativa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAASAPPAPADALPKGADSFFRTVISNMEKVYLSRNPTAKTILELVRSYD
GDHICYDHFAFRTFGVDGYGIKSLAEFFTDFGYVPREELRFPAKKLRALW
FSPPTNDGYTGTGVYGPLPRIFISELLVDELSPQSQDIIQKYIRTSGKGN
KHATLASTSGELTWEKPIYSDFQVLSRESEYAAWTLVNGYALNHTTISTH
RLISDIRSINKFNKFVEDNGFKLNSEGGILKVSPDGLLQQSSTVADSALF
TFADGITESIPRSYIEFAERLVLPQFKDLPNDEVNEHHRRDGFEVGNADK
IFESTSNDQLTR
Ligand information
Ligand IDOOG
InChIInChI=1S/C6H8O5/c7-4(6(10)11)2-1-3-5(8)9/h1-3H2,(H,8,9)(H,10,11)
InChIKeyFGSBNBBHOZHUBO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(CC(=O)C(=O)O)CC(=O)O
ACDLabs 12.01O=C(C(=O)O)CCCC(=O)O
CACTVS 3.385OC(=O)CCCC(=O)C(O)=O
FormulaC6 H8 O5
Name2-OXOADIPIC ACID
ChEMBL
DrugBank
ZINCZINC000001532613
PDB chain6w1k Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6w1k An iron (II) dependent oxygenase performs the last missing step of plant lysine catabolism.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		H60 R64 N195 H196 Q242 Y266 E268 A300 F304
Binding residue
(residue number reindexed from 1)		H58 R62 N193 H194 Q240 Y264 E266 A298 F302
Annotation score5
Enzymatic activity
Enzyme Commision number 1.13.11.93: 2-oxoadipate dioxygenase/decarboxylase.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:6w1k, PDBe:6w1k, PDBj:6w1k
PDBsum6w1k
PubMed32523014
UniProtQ337M4|HGLS_ORYSJ 2-oxoadipate dioxygenase/decarboxylase, chloroplastic/amyloplastic (Gene Name=FLO7)

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