Structure of PDB 6vyp Chain A Binding Site BS01

Receptor Information
>6vyp Chain A (length=110) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TMQTARKSTGGKAPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREI
AQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDI
QLARRIRGER
Ligand information
>6vyp Chain I (length=191) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcgaccctatacgcggccgccctggagaatcccggtgccgaggccgctc
aattggtcgtagacagctctagcaccgcttaaacgcacgtacgcgctgtc
ccccgcgttttaaccgccaaggggattactccctagtctccaggcacgtg
tcagatatatacatcctgtgcatgtattgaacagcgacgat
Receptor-Ligand Complex Structure
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PDB6vyp Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate.
Resolution4.99 Å
Binding residue
(original residue number in PDB)
H39 R42 R72 R83 F84 Q85 R116 V117 T118 M120
Binding residue
(residue number reindexed from 1)
H15 R18 R48 R59 F60 Q61 R92 V93 T94 M96
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6vyp, PDBe:6vyp, PDBj:6vyp
PDBsum6vyp
PubMed32396821
UniProtP84233|H32_XENLA Histone H3.2

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