Structure of PDB 6vjw Chain A Binding Site BS01

Receptor Information
>6vjw Chain A (length=138) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPS
AEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGI
GKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6vjw Catalytic mechanism of the mismatch-specific DNA glycosylase methyl-CpG-binding domain 4.
Resolution2.02 Å
Binding residue
(original residue number in PDB)		L466 N467 R468 G536 G538 Y540 G541 D560 K562
Binding residue
(residue number reindexed from 1)		L29 N30 R31 G99 G101 Y103 G104 D123 K125
Enzymatic activity
Enzyme Commision number 3.2.2.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair

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Molecular Function
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Biological Process
External links
PDB RCSB:6vjw, PDBe:6vjw, PDBj:6vjw
PDBsum6vjw
PubMed32297632
UniProtO95243|MBD4_HUMAN Methyl-CpG-binding domain protein 4 (Gene Name=MBD4)

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