Structure of PDB 6vfr Chain A Binding Site BS01

Receptor Information

>6vfr Chain A (length=428) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPLL
VVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEV
LDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLS
ANDFFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRS
GSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGA
NGKIVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQ
DLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDT
FVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNATLDREK
RSEYSLTVIAEDRGTPSLSTVKHFTVQI

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

6vfr Chain A Residue 510 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6vfr Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Resolution	2.79 Å
Binding residue (original residue number in PDB)	N104 N106 D136 D138 N142 D193
Binding residue (residue number reindexed from 1)	N104 N106 D136 D138 N142 D193
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6vfr, PDBe:6vfr, PDBj:6vfr
PDBsum	6vfr
PubMed	32101743
UniProt	Q9HCL0\|PCD18_HUMAN Protocadherin-18 (Gene Name=PCDH18)

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