Structure of PDB 6vaa Chain A Binding Site BS01

Receptor Information
>6vaa Chain A (length=1168) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDQKILSLAAEKTADKLQEFLQTLREGDLTNLLQNQAVKGKVAGALLRAI
FKGSPCSEEAGTLRRRKIYTCCIQLVESGDLQKEIVSEIIGLLMLEAHHF
PGPLLVELANEFISAVREGSLVNGKSLELLPIILTVLATKKENLAYLSGE
ECKKQLINTLCSGRWDQQYVIQLTSMFKDVPLTAEEVEFVVEKALSMFSK
MNLQEIPPLVYQLLVLSSKGSRKSVLEGIIAFFSALDKQHNEEQSPSGEL
RHVEGTIILHIVFAIKLDYELGRELVKHLKVGQQGDSNNNLSPFSIALLL
SVTRIQRFQDQVLDLLKTSVVKSFKDLQLLQGSKFLQNLVPHRSYVSTMI
LEVVKNSVHSWDHVTQGLVELGFILMDSYGPKKVLPSLSRMPNQHACKLG
ANILLETFKIHEMIRQEILEQVLNRVVTRASSPISHFLDLLSNIVMYAPL
VLQNCSSKVTEAFDYLSFLPLQTVQRLLKAVQPLLKVSMSMRDCLILVLR
KAMFANQLDARKSAVAGFLLLLKNFKVLYNSVANETFCLEIMDSLRRCLS
QQADVRLMLYEGFYDVLRRNSQLANSVMQTLLSQLKQFYEPEPDLLPPLK
LEACILTQGDQISLQEPLDYLLCCIQHCLAWYKNTVIPEAFYEDLDDILE
SITNRMIKSELEDFELDKSADFSQSTSIGIKNNISAFLVMGVCEVLIEYN
FSISSFSKNRFEDILSLFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSM
KFVSSLLTALFRDSIQSHQESLSVLRSSNEFMRYAVNVALQKVQQLKETG
HVSGPDGQNPEKIFQNLCDLTRVLLWRYTSIPTSVEESGKKEKGKSISLL
CLEGLQKIFSAVQQFYQPKIQQFLRALVSVTQRTAFQIRQFQRSLLNLLS
SQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSRED
ALFCKSLMNLLFSLHVSYKSPVILLRDLSQDIHGHLGDIDQDVEVEKTNH
FAIVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKLKGQVPNQPVEKAIIM
QLGTLLTFFHELVQTALPSGSCVDTLLKDLCKMYTTLTALVRYYLQVCQS
SGGIPKNMEKLVKLSGSHLTPLCYSFISYVQNKSTKPIPNLIFAIEQYEK
FLIHLSKKSKVSLMQHMK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6vaa DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		G790 K793
Binding residue
(residue number reindexed from 1)		G733 K736
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0070182 DNA polymerase binding
Biological Process
GO:0006281 DNA repair
GO:0031398 positive regulation of protein ubiquitination
GO:0036297 interstrand cross-link repair
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:1990391 DNA repair complex

View graph for
Molecular Function
View graph for
Biological Process
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Cellular Component
External links
PDB RCSB:6vaa, PDBe:6vaa, PDBj:6vaa
PDBsum6vaa
PubMed32269332
UniProtQ9NVI1|FANCI_HUMAN Fanconi anemia group I protein (Gene Name=FANCI)

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