Structure of PDB 6v5a Chain A Binding Site BS01

Receptor Information
>6v5a Chain A (length=594) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEAPFK
RHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIM
RVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKEGDDAICLAELKLG
FIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVSNEMYTEYLS
SAFVGLSFPTVCELCFVKLKLLMIAIEYSRILINPGNHLKIQEGTLGFFI
ASDAKEVKRAFFYCKDSNVKKYDSTGMFHWCAPKEIEKVILTRSEAAMTV
LSGHVVVCIFGDVSSALIGLRNLVMPLRASNFHYHELKHIVFVGSIEYLK
REWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQDKECILA
SLNIKSMQFDSITTGVNIPIITELVNDTNVQFLDQDDDDDPDTELYLTQP
FACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGAEALIAEENALRGG
YSTPQTLANRDRCRVAQLALLDGPFADLGDGGCYGDLFCKALKTYNMLCF
GIYRLRDAPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDSNSL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6v5a Chain A Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6v5a Coupling of Ca2+and voltage activation in BK channels through the alpha B helix/voltage sensor interface.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		Q889 D892 D895 D897
Binding residue
(residue number reindexed from 1)		Q431 D434 D437 D439
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006813 potassium ion transport
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:6v5a, PDBe:6v5a, PDBj:6v5a
PDBsum6v5a
PubMed32513714
UniProtQ12791|KCMA1_HUMAN Calcium-activated potassium channel subunit alpha-1 (Gene Name=KCNMA1)

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