Structure of PDB 6v4e Chain A Binding Site BS01
Receptor Information
>6v4e Chain A (length=90) Species:
7955
(Danio rerio) [
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LPGEGTQVHPRAPLLQILKVAGAQEEVFTVKEVMHYLGQYIMMKQLYDKQ
RQHIVHCHDDPLGELLEVGSFSVKNPSPLYEMLKRNLVIL
Ligand information
>6v4e Chain C (length=13) Species:
9606
(Homo sapiens) [
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QQTFNLWRLLKQN
Receptor-Ligand Complex Structure
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PDB
6v4e
Identification of a Structural Determinant for Selective Targeting of HDMX.
Resolution
1.62 Å
Binding residue
(original residue number in PDB)
K47 M50 H51 G54 I57 Y63 Q68 H69 V89
Binding residue
(residue number reindexed from 1)
K31 M34 H35 G38 I41 Y47 Q52 H53 V73
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0043066
negative regulation of apoptotic process
GO:0051726
regulation of cell cycle
Cellular Component
GO:0005634
nucleus
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Biological Process
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Cellular Component
External links
PDB
RCSB:6v4e
,
PDBe:6v4e
,
PDBj:6v4e
PDBsum
6v4e
PubMed
32359398
UniProt
Q7ZUW7
|MDM4_DANRE Protein Mdm4 (Gene Name=mdm4)
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