Structure of PDB 6uv1 Chain A Binding Site BS01

Receptor Information
>6uv1 Chain A (length=438) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVC
PKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQ
TGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADD
YGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNL
RRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQL
AEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAE
KENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRS
GKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKG
TAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6uv1 RNA Specificity and Autoregulation of DDX17, a Modulator of MicroRNA Biogenesis.
Resolution2.307 Å
Binding residue
(original residue number in PDB)		P173 R175 G201 G202 T222 P223 G224 R225 D228 F256 Q259 E347 T348 K349 H370 G371 R378 T396 N418
Binding residue
(residue number reindexed from 1)		P136 R138 G164 G165 T185 P186 G187 R188 D191 F219 Q222 E310 T311 K312 H333 G334 R341 T359 N381
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6uv1, PDBe:6uv1, PDBj:6uv1
PDBsum6uv1
PubMed31851931
UniProtQ92841|DDX17_HUMAN Probable ATP-dependent RNA helicase DDX17 (Gene Name=DDX17)

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