Structure of PDB 6uts Chain A Binding Site BS01

Receptor Information
>6uts Chain A (length=229) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVINDDVIEA
GQGFGTHPHKDMEILTYVLEGTVEHQDSGNKEQVPAGEFQIMSAGTGIRH
SEYNPSSTERLHLYQIWIMPEENGITPRYEQRRFAVQGKQLVLSPDARDG
SLKVHQDMELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGVKASTS
DGLAIWDEQAISIHADSDSEVLLFDLPPV
Ligand information
Ligand IDNI
InChIInChI=1S/Ni/q+2
InChIKeyVEQPNABPJHWNSG-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ni++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ni+2]
FormulaNi
NameNICKEL (II) ION
ChEMBL
DrugBankDB14204
ZINC
PDB chain6uts Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6uts Structure-Dependent Modulation of Substrate Binding and Biodegradation Activity of Pirin Proteins toward Plant Flavonols.
Resolution3.09 Å
Binding residue
(original residue number in PDB)		H57 H59 H101
Binding residue
(residue number reindexed from 1)		H57 H59 H100
Annotation score1
Enzymatic activity
Enzyme Commision number 1.13.11.24: quercetin 2,3-dioxygenase.
Gene Ontology
Molecular Function
GO:0008127 quercetin 2,3-dioxygenase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity

View graph for
Molecular Function
External links
PDB RCSB:6uts, PDBe:6uts, PDBj:6uts
PDBsum6uts
PubMed31609578
UniProtP46852|YHHW_ECOLI Quercetin 2,3-dioxygenase (Gene Name=yhhW)

[Back to BioLiP]