Structure of PDB 6uls Chain A Binding Site BS01
Receptor Information
>6uls Chain A (length=124) Species:
9606
(Homo sapiens) [
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TNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELPT
Ligand information
>6uls Chain B (length=10) Species:
9606
(Homo sapiens) [
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HPGKGVKSPG
Receptor-Ligand Complex Structure
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PDB
6uls
BET-Family Bromodomains Can Recognize Diacetylated Sequences from Transcription Factors Using a Conserved Mechanism.
Resolution
1.5 Å
Binding residue
(original residue number in PDB)
Q78 W81 V87 L92 Y139 N140 D145 I146 M149
Binding residue
(residue number reindexed from 1)
Q36 W39 V45 L50 Y97 N98 D103 I104 M107
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6uls
,
PDBe:6uls
,
PDBj:6uls
PDBsum
6uls
PubMed
33620209
UniProt
O60885
|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)
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