Structure of PDB 6uln Chain A Binding Site BS01

Receptor Information
>6uln Chain A (length=273) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHSMRYFYTAVSRPGRGEPRFIAVGYVDDTQFVQFDSDAASPRGEPRAPW
VEQEGPEYWDRETQKYKRQAQTDRVSLRNLRGYYNQSEAGSHTLQRMYGC
DLGPDGRLLRGYNQFAYDGKDYIALNEDLRSWTAADKAAQITQRKWEAAR
EAEQRRAYLEGTCVEWLRRYLENGKKTLQRAEHPKTHVTHHPVSDHEATL
RCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPS
GEEQRYTCHVQHEGLPEPLTLRW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6uln High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D.
Resolution2.01 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 R69 T73 V76 S77 N80 Y84 Y99 T143 K146 W147 E152 R156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 E62 K65 R68 T72 V75 S76 N79 Y83 Y98 T142 K145 W146 E151 R155 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number ?
External links