Structure of PDB 6uj9 Chain A Binding Site BS01
Receptor Information
>6uj9 Chain A (length=277) Species:
9606
(Homo sapiens) [
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MGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRA
PWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY
GCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEA
AREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>6uj9 Chain C (length=10) Species:
9606
(Homo sapiens) [
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SPNGTIQNIL
Receptor-Ligand Complex Structure
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PDB
6uj9
Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
Y7 Y59 N63 I66 Y67 A69 Q70 E76 S77 N80 Y84 Y99 Y116 T143 W147 E152 Q155 R156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y8 Y60 N64 I67 Y68 A70 Q71 E77 S78 N81 Y85 Y100 Y117 T144 W148 E153 Q156 R157 Y160 W168 Y172
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6uj9
,
PDBe:6uj9
,
PDBj:6uj9
PDBsum
6uj9
PubMed
34489470
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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