Structure of PDB 6uj7 Chain A Binding Site BS01
Receptor Information
>6uj7 Chain A (length=280) Species:
9606
(Homo sapiens) [
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GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
REAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEPSSQS
Ligand information
>6uj7 Chain C (length=10) Species:
9606
(Homo sapiens) [
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SPNGTIQNIL
Receptor-Ligand Complex Structure
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PDB
6uj7
Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
Resolution
1.9 Å
Binding residue
(original residue number in PDB)
Y7 Y59 N63 I66 Q70 T73 E76 S77 N80 Y84 Y99 Y116 Y123 T143 W147 E152 R156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y59 N63 I66 Q70 T73 E76 S77 N80 Y84 Y99 Y116 Y123 T143 W147 E152 R156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6uj7
,
PDBe:6uj7
,
PDBj:6uj7
PDBsum
6uj7
PubMed
34489470
UniProt
P01889
|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)
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