Structure of PDB 6ue4 Chain A Binding Site BS01

Receptor Information
>6ue4 Chain A (length=354) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PDYEYEIKPGDNLSTIFNQLGFAYTELMKVMETDLNYLALDTLRPGNVLR
FWKGSDNTLAKMELEFSLVDRAVYTRLNDGSYEFEERKIPGTWKVEPLIG
EVDGSFSLSANRAGLGAADVDQIVTLLKDKINFGRDLRRGDRFEVVLSRQ
LVGEKLTGNSEIQAIKIFNRGKEITAYLHQDGQYYDKNGDSLQRAFQRYP
VDSKWRISSNFDPRRLHPVTKRVAPHNGTDFAMPIGTPVYTSGDGVVVMT
RNHPYAGNYVVIQHGNTYMTRYLHLSKILVKKGQKVSRGQRIGLSGNTGR
VTGPHLHYELIVRGRPVNAMKANIPMASSVPKKEMAQFIAKRKELDQMLA
RQES
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6ue4 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6ue4 Structural basis of peptidoglycan endopeptidase regulation.
Resolution2.08 Å
Binding residue
(original residue number in PDB)		H297 D301 H378
Binding residue
(residue number reindexed from 1)		H226 D230 H307
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0004222 metalloendopeptidase activity
GO:0016787 hydrolase activity
GO:0042834 peptidoglycan binding
GO:0046872 metal ion binding
Biological Process
GO:0000920 septum digestion after cytokinesis
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ue4, PDBe:6ue4, PDBj:6ue4
PDBsum6ue4
PubMed32393643
UniProtQ9KN86

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