Structure of PDB 6u8h Chain A Binding Site BS01
Receptor Information
>6u8h Chain A (length=128) Species:
9606
(Homo sapiens) [
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GSEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPD
YHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDI
VLMAQTLEKIFLQKVASMPQEEQELVVT
Ligand information
>6u8h Chain C (length=12) Species:
9606
(Homo sapiens) [
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WSWLCKKYNLIH
Receptor-Ligand Complex Structure
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PDB
6u8h
Cyclic peptides can engage a single binding pocket through highly divergent modes.
Resolution
2.07 Å
Binding residue
(original residue number in PDB)
W97 P98 F99 Q101 V103 L108 L110 N156 I162
Binding residue
(residue number reindexed from 1)
W35 P36 F37 Q39 V41 L46 L48 N94 I100
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6u8h
,
PDBe:6u8h
,
PDBj:6u8h
PDBsum
6u8h
PubMed
33046654
UniProt
P25440
|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)
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