Structure of PDB 6u75 Chain A Binding Site BS01

Receptor Information
>6u75 Chain A (length=261) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LFTSPFYKPIVQIPDANKKLKQSAGRGCTKMKFKVSKSNHDLLKSNKSYK
LYLFSGFSIPFIYETVGHEAIDFPYPCELVFNGTKLEDNVKGLKKQNGTG
NPANLTPYLKVPTEMNHLDLHYLNIDKEYSISCFIVEVFSPEALLGKILK
RPKIIKQATTAYIKRTLNEQTSTVLSLQCPISCTRMKYPAKTDQCKHIQC
FDALWFLHSQSQVPTWQCPICQHPIKFDQLKISEFVDNIIQNCNEDVEQV
EISVDGSWKPI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6u75 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6u75 DNA asymmetry promotes SUMO modification of the single-stranded DNA-binding protein RPA.
Resolution2.63 Å
Binding residue
(original residue number in PDB)		C354 H356 C377 C380
Binding residue
(residue number reindexed from 1)		C195 H197 C218 C221
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.-
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:6u75, PDBe:6u75, PDBj:6u75
PDBsum6u75
PubMed34585421
UniProtQ12216|SIZ2_YEAST E3 SUMO-protein ligase SIZ2 (Gene Name=NFI1)

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