Structure of PDB 6u6k Chain A Binding Site BS01
Receptor Information
>6u6k Chain A (length=126) Species:
9606
(Homo sapiens) [
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STNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTE
Ligand information
>6u6k Chain C (length=11) Species:
32630
(synthetic construct) [
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WWIIPKVKKGC
Receptor-Ligand Complex Structure
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PDB
6u6k
Cyclic peptides can engage a single binding pocket through highly divergent modes.
Resolution
1.7 Å
Binding residue
(original residue number in PDB)
F79 W81 V87 L92 N140 D144 D145 I146 M149
Binding residue
(residue number reindexed from 1)
F38 W40 V46 L51 N99 D103 D104 I105 M108
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6u6k
,
PDBe:6u6k
,
PDBj:6u6k
PDBsum
6u6k
PubMed
33046654
UniProt
O60885
|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)
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