Structure of PDB 6u43 Chain A Binding Site BS01

Receptor Information
>6u43 Chain A (length=723) Species: 1392998 (Candidatus Methanoperedens nitroreducens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GMGRRKKMVERVTTLMDKPEFIRNIGIVAHIDHGKTTLSDNLLAGAGMIS
LFMDFDEEEQKRGITIDSANVSMVHEYEGKEYLINLIDTPGHVDFGGDVT
RAMRAVDGAVVVVDAVEGAMPQTETVLRQALRENVVPILFINKVDRLIME
LKLTPQDMQIRLGAVIDKINKLIKGMKPDSYDGLRLDAAVGKVAFGSALN
NWAISVPFMKKTGIGFKEVIEYCMEDQQQKLAERCPLHAVVNDMVIRFLP
NPVQAQKERIKVIWHGDKGSEIGKSMANVDPNGKVALMITDISTDPHAGE
VATGRLFSGTLERGKEVYISGMPNPNRIQQVGLFMGPERIEVDRITAGNI
VAVTGLADAIVGSTASTDKAMVPFESIRHVSEPVVTVAVEAKHMKDLPKL
VEVLRQVAKEDPTLKVTINQETGEHLLAGMGELHLEIVAHRIQRDKHVEI
TTSKPLVVYRETVSAHAGPVEGKSPNRHNRFYIEIEPLQPAIFELVRNGE
ISMKQQEVERRDILMKAGMSKEEAKGITHISENNIFIDMTKGIQYLNETM
ELVLEGFEEVIKGGPLSREPVMGLKVKLMDAKLHEDSINRGPAQVIPASR
QAIQAAMLMAGATLLEPFQKVFIHVPQEQMGGAMREIQGRRGAILDMKTE
GDTTIIEAKAPVAQLFGFAGDIRSATEGRAMWSTEFLGFEPIPANMLAET
VMGIRQRKGLKLEMPKPSDFISP
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6u43 Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6u43 Structural basis of elongation factor 2 switching
Resolution1.4 Å
Binding residue
(original residue number in PDB)		T35 T71
Binding residue
(residue number reindexed from 1)		T36 T65
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0006414 translational elongation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6u43, PDBe:6u43, PDBj:6u43
PDBsum6u43
PubMed
UniProtA0A062V290

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