Structure of PDB 6tzy Chain A Binding Site BS01

Receptor Information
>6tzy Chain A (length=275) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FSGVVDIIVVRQPDDSLKSMPFHIRFGTLKNQNINIQITVNDKKIEDVFM
LMLPEGACYFPELNAKNEIQKKLRPSSAILKKFNLKNGYNKIQFIAESDL
QGKQLIEGKIYLYNYDTKLVISDVDGTVTKSDWTHDDIAELYTNIQKNGY
KMVYLSSRPLYFYNYTQGYLKGIIQNGFTMPDGPILLSPDQIISSEFKGA
LLKDLRRVFPEEVNPIFAGFGNRDTDATACLYAGVIIDNIFIINEQSQVE
ILGKQEKSSYKKINEKIQELFPRLP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6tzy Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6tzy Crystal Structure of a lipin/Pah Phosphatidic Acid Phosphatase
Resolution3.0 Å
Binding residue
(original residue number in PDB)		D146 K244 N268 D272
Binding residue
(residue number reindexed from 1)		D123 K198 N222 D226
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008195 phosphatidate phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0044255 cellular lipid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6tzy, PDBe:6tzy, PDBj:6tzy
PDBsum6tzy
PubMed
UniProtI7MFJ3

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