Structure of PDB 6tz2 Chain A Binding Site BS01

Receptor Information
>6tz2 Chain A (length=1208) Species: 110829 (Bombyx mori cypovirus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TELYNTIFSETRKFTRESFKEIEHLTAKLANDRVARHDFLFNNSIALISD
YSGEDSNGNQLQATVTIPNEITNPKEYDPSDYPLAEDESFFKQGHKYDYL
VTFRAGSLTNTYEPKTKMYKLHAALDKLMHVKQRKSRFADLWRELCAVIA
SLDVWYQTTNYPLRTYVKLLFHKGDEFPFYESPSQDKIIFNDKSVASILP
TFVYTCCQVGTAIMSGILTHVESIVAMNHFLHCAKDSYIDEKLKIKGIGR
SWYQEALHNVGRATVPVWSQFNEVIGHRTKTTSEPHFVSSTFISLRAKRA
ELLYPEFNEYINRALRLSKTQNDVANYYAACRAMTNDGTFLATLTELSLD
AAVFPRIEQRLVTRPAVLMSNTRHESLKQKYANGVGSIAQSYLSSFTDEI
AKRVNGIHHDEAWLNFLTTSSPGRKLTEIEKLEVGGDVAAWSNSRIVMQA
VFAREYRTPERIFKSLKAPIKLVERQQSDRRQRAISGLDNDRLFLSFMPY
TIGKQIYDLNDNAAQGKQAGNAFDIGEMLYWTSQRNVLLSSIDVAGMDAS
VTTNTKDIYNTFVLDVASKCTVPRFGPYYAKNMEVFEVGKRQSQVKYVNA
AWQACALEAANSQTSTSYESEIFGQVKNAEGTYPSGRADTSTHHTVLLQG
LVRGNELKRASDGKNSCLTTIKILGDDIMEIFQGNENDTHDHAVSNASIL
NESGFATTAELSQNSIVLLQQLVVNGTFWGFADRISLWTREDTKDIGRLN
LAMMELNALIDDLLFRVRRPEGLKMLGFFCGAICLRRFTLSVDNKLYDST
YNNLSKYMTLVKYDKNPDFDSTLMSLILPLAWLFMPRGGEYPAYPFERRD
GTFTEDESMFTARGAYKRRLLYDVSNIREMIQQNSMVLDDDLLHEYGFTG
ALLLIDLNILDLIDEVKKEDISPVKVNELATSLEQLGKLGEREKSRRAAS
DLKIRGHALSNDIVYGYGLQEKIQKSAMATKETTVQSKRVSSRLHEVIVA
KTRDYKIPTMPADALHLYEFEVEDVTVDLLPHAKHTSYSNLAYNMSFGSD
GWFAFALLGGLDRSANLLRLDVASIRGNYHKFSYDDPVFKQGYKIYKSDA
TLLNDFFVAISAGPKEQGILLRAFAYYSLYGNVEYHYVLSPRQLFFLSDN
PVSAERLVRIPPSYYVSTQCRALYNIFSYLHILRSITSNQGKRLGMVLHP
GLIAYVRG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6tz2 Conservative transcription in three steps visualized in a double-stranded RNA virus.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		T422 R484 L678 D681 Q724 I739 E759 D766 K976 N1070 R1073 H1084 K1085
Binding residue
(residue number reindexed from 1)		T418 R480 L674 D677 Q720 I735 E755 D762 K972 N1066 R1069 H1080 K1081
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0019079 viral genome replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6tz2, PDBe:6tz2, PDBj:6tz2
PDBsum6tz2
PubMed31695188
UniProtQ993A4

[Back to BioLiP]