Structure of PDB 6tux Chain A Binding Site BS01

Receptor Information
>6tux Chain A (length=330) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSI
ENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASQ
KQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQT
SGTITDDSAIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLIN
LAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQKNP
KNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLD
KIREFCQRYFGWNRTKTDESLFPVLKQLDA
Ligand information
Receptor-Ligand Complex Structure
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PDB6tux The crystal structure of human XPG, the xeroderma pigmentosum group G endonuclease, provides insight into nucleotide excision DNA repair.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		P867 G870 V872 T873
Binding residue
(residue number reindexed from 1)		P214 G217 V219 T220
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0004519 endonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0006289 nucleotide-excision repair
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6tux, PDBe:6tux, PDBj:6tux
PDBsum6tux
PubMed32821917
UniProtP28715|ERCC5_HUMAN DNA excision repair protein ERCC-5 (Gene Name=ERCC5)

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