Structure of PDB 6thk Chain A Binding Site BS01

Receptor Information
>6thk Chain A (length=466) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDLIQREIYLQKNIYYPVRSIFEQGTKEKKEINKKVSDQVDGLLKQITQG
KREATRQERVDVMSAVLHKMESDLEGYKKTFTKGPFIDYEKQSSLSIYEA
WVKIWEKNSWEERKKYPFQQLVRDELERAVAYYKQDSLSEAVKVLRQELN
KQKALKEKEDLSQLERDYRTRKANLQMKVQSELDQAGSALPPLVSPTPEQ
WLERATRLVTQAIADKKQLQTTNNTLIKNSPTPLEKQKAIYNGELLVDEI
ASLQARLVKLNAETTRRRTEAERKAAEEQALQDAIKFTADFYKEVTEKFG
ARTSEMARQLAEGARGKNIRSSAEAIKSFEKHKDALNKKLSLKDRQAIAK
AFDSLDKQMMAKSLEKFSKGFGVVGKAIDAASLYQEFKISTETGDWKPFF
VKIETLAAGAAASWLVGIAFATATATPIGILGFALVMAVTGAMIDEDLLE
KANNLVISILEHHHHH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6thk Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6thk Pyocin S5 Import into Pseudomonas aeruginosa Reveals a Generic Mode of Bacteriocin Transport.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D383 H501 H503
Binding residue
(residue number reindexed from 1)		D344 H462 H464
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0140911 pore-forming activity
Biological Process
GO:0031640 killing of cells of another organism
GO:0050829 defense response to Gram-negative bacterium
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6thk, PDBe:6thk, PDBj:6thk
PDBsum6thk
PubMed32156826
UniProtQ9I4Y4

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