Structure of PDB 6su5 Chain A Binding Site BS01

Receptor Information
>6su5 Chain A (length=154) Species: 1442384 (Thermus phage 2119) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RILEPWNRWYRQKGVYRIRGTPPHYIVLHHTAGPVDQAPEVIRDFHEKGR
GWPHIGYHYLVYQDGRVYKTLPNNAIPICVREFNPVSLCIAAVGDFSQGP
AWPDNAPGWKALLELKDALVKAYPKAVLVLHKELTQTTCPGVLSWGMVAE
KGGK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6su5 Chain A Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6su5 Molecular Characterization of a Novel Lytic Enzyme LysC from Clostridium intestinale URNW and Its Antibacterial Activity Mediated by Positively Charged N -Terminal Extension.
Resolution1.2 Å
Binding residue
(original residue number in PDB)		H30 H132 C140
Binding residue
(residue number reindexed from 1)		H29 H131 C139
Annotation score4
Enzymatic activity
Enzyme Commision number 3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
GO:0046872 metal ion binding
Biological Process
GO:0009253 peptidoglycan catabolic process
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium

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Molecular Function
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Biological Process
External links
PDB RCSB:6su5, PDBe:6su5, PDBj:6su5
PDBsum6su5
PubMed32664473
UniProtW0FBY3

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