Structure of PDB 6ssc Chain A Binding Site BS01

Receptor Information
>6ssc Chain A (length=149) Species: 36845 (Clostridium intestinale) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TPKIVEVNYTWATPLSYNFNPNMIVYHHTVDNNMTPQKIDEIHKQRGWSG
IGYHFYIRKDGTIYRGRPENAVGSHAPGVNARAFGIASEGNFNEEYVTPQ
QMTSLIALSRYLMNKYNITDLKRHKDVRQTECPGNNFPFEEIKAKLNVK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6ssc Chain A Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6ssc Molecular Characterization of a Novel Lytic Enzyme LysC from Clostridium intestinale URNW and Its Antibacterial Activity Mediated by Positively Charged N -Terminal Extension.
Resolution1.21 Å
Binding residue
(original residue number in PDB)		H50 H147 C155
Binding residue
(residue number reindexed from 1)		H27 H124 C132
Annotation score4
Enzymatic activity
Enzyme Commision number 3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
GO:0046872 metal ion binding
Biological Process
GO:0009253 peptidoglycan catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6ssc, PDBe:6ssc, PDBj:6ssc
PDBsum6ssc
PubMed32664473
UniProtU2NM08

[Back to BioLiP]