Structure of PDB 6sr6 Chain A Binding Site BS01

Receptor Information
>6sr6 Chain A (length=519) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APGERVVIGITFGNSNSSIAHTVDDKAEVIANEDGDRQIPTILSYVDGDE
YYGQQAKNFLVRNPKNTVAYFRDILGQDFKSVDPTHNHASAHPQEAGDNV
VFTIKDKAEEDAEPSTLTVSEIATRYLRRLVGAASEYLGKKVTSAVITIP
TNFTEKQKAALIAAAAAADLEVLQLISEPAAAVLAYDARPEATISDKIIV
VADLGGSRSDVTVLASRSGMYTILATVHDYEYHGIALDKVLIDHFSKEFL
KKNPGAKDPRENPRSLAKLRLEAESTKRALSRSTNASFSVESLIDGLDFA
STINRLRYETIARTVFEGFNRLVESAVKKAGLDPLDVDEVIMSGGTSNTP
RIAANFRYIFPESTRILAPSTDPSALNPSELQARGAALQASLIQEFETED
IEQSTHAAVTTMPHVTNAIGVVSVSEKFVPIIAPETAVPARRTVHLDAPK
EGGDVLVKVVEGSTHINVREKVWKIGSTLAEAAVRGVKKGAKVEVTINVN
TDLTVIVTAREVGVRGTLS
Ligand information
Ligand IDATP
InChIInChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKeyZKHQWZAMYRWXGA-KQYNXXCUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(=O)O[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 10.04O=P(O)(O)OP(=O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
FormulaC10 H16 N5 O13 P3
NameADENOSINE-5'-TRIPHOSPHATE
ChEMBLCHEMBL14249
DrugBankDB00171
ZINCZINC000004261765
PDB chain6sr6 Chain A Residue 700 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6sr6 The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		N22 S23 N24 G213 G214 S215 E282 K285 R286 S289 G352 G353 N356
Binding residue
(residue number reindexed from 1)		N14 S15 N16 G205 G206 S207 E274 K277 R278 S281 G344 G345 N348
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6sr6, PDBe:6sr6, PDBj:6sr6
PDBsum6sr6
PubMed32198371
UniProtG0RZX9

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