Structure of PDB 6skj Chain A Binding Site BS01

Receptor Information
>6skj Chain A (length=387) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLP
QGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRP
PGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKK
LRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNP
RKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLL
TRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTL
PSTIMNKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLME
NKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6skj High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		V181 D183 D185 F188 F190 N246 T282 A283 Y296 H298 F311 S405 I469 G470 D471 G472
Binding residue
(residue number reindexed from 1)		V78 D80 D82 F85 F87 N143 T179 A180 Y193 H195 F208 S302 I362 G363 D364 G365
Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.97: glycylpeptide N-tetradecanoyltransferase.
Gene Ontology
Molecular Function
GO:0004379 glycylpeptide N-tetradecanoyltransferase activity
Biological Process
GO:0006499 N-terminal protein myristoylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6skj, PDBe:6skj, PDBj:6skj
PDBsum6skj
PubMed32111831
UniProtP30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (Gene Name=NMT1)

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