Structure of PDB 6sj0 Chain A Binding Site BS01

Receptor Information

>6sj0 Chain A (length=493) Species: 1931 (Streptomyces sp.) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MGARLITGGTVYTADAQESVHARGAVLTVDDKVVAVGPAVEVEQAVQALD
PAVRAELRRLDASRMMVLPGFVNAHWHEMFAMGFTMRGALRPPSDRADQV
AFMGGGGDMHQISATFDRFDGLIEAMTEDEARAIAEYSMWIQLRGGVTTL
GDMGSLNRPLAMVEAARRLGMRFSASTWASDAVLAPDRSRFLRTRDADTV
LASFEALLGAVAADPTGRIRCRPNVSYVTNMTDELARGMAELVERHDLPF
ATHVGALRNEADAMRAYHGETGVRRLAEAGLVDERLMAGHSAFLDDQEQK
LMLAGRAHISHSPGKYGPSGESALTETGVVPALRRAGLDVSLSTDAAALP
GAGIAETMRAAWQMYNEMSADQTEVLPTDALAMATRIAAKGLRWDDAVGS
LEPGKQADLLLVRTDDWRYLLNPRPLESFLWLAGSADVDTVIVGGRTLVE
GGRGVEVDEAALRDRYLQALRGFTTRALRVPAEAVDPVLAEVA

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

6sj0 Chain A Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	6sj0 The Biosynthesis of the Benzoxazole in Nataxazole Proceeds via an Unstable Ester and has Synthetic Utility.
Resolution	1.75 Å
Binding residue (original residue number in PDB)	H75 H77 H253 D345
Binding residue (residue number reindexed from 1)	H75 H77 H253 D345
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0016787	hydrolase activity
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:6sj0, PDBe:6sj0, PDBj:6sj0
PDBsum	6sj0
PubMed	31903677
UniProt	A0A022MQ12

[Back to BioLiP]