Structure of PDB 6sei Chain A Binding Site BS01

Receptor Information
>6sei Chain A (length=276) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QCKPIPALYTVYVLRSTVRHASLYIGSTPNPPRRLKQHNGLVPGGAARTS
RSSLRPWEMVALVSGFPSMVAALKFQWALTNPHLSVHIPSASRRPQRPPR
SLASVVANLHLLLRVPSFARWPLRVHFFRRDVFAAWEKWCAAASERLRPS
LAVVTDFEGGSPCWGIHALPLDYEPIKDYVAKGQEIFEFERQGACVVCRE
EMASGDGLQALCTNQGCDGVGHLSCWSRHFLKEADSILPVQGQCPKCGGE
MEWGNMMKELTLRTRGQKEVEKLLKR
Ligand information
Receptor-Ligand Complex Structure
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PDB6sei Recognition and processing of branched DNA substrates by Slx1-Slx4 nuclease.
Resolution2.69 Å
Binding residue
(original residue number in PDB)
R22 H23 R51 R54 S56 R111
Binding residue
(residue number reindexed from 1)
R19 H20 R48 R51 S53 R97
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0008821 crossover junction DNA endonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006281 DNA repair
GO:0006310 DNA recombination
Cellular Component
GO:0005634 nucleus
GO:0033557 Slx1-Slx4 complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6sei, PDBe:6sei, PDBj:6sei
PDBsum6sei
PubMed31584081
UniProtG2QV68

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