Structure of PDB 6sdo Chain A Binding Site BS01

Receptor Information

>6sdo Chain A (length=360) Species: 5693 (Trypanosoma cruzi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYF
RGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDI
MDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLK
DLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIY
KRIVKYKTTFYTYLLPLVMGLLVSEAAASVEMNLVERVAHLIGEYFQVQD
DVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGEK
DPAKVAVVKRLYSKANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESV
AVVWEKTHKR

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

6sdo Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6sdo Trypanosoma cruzi farnesyl diphosphate synthase in complex with 3np
Resolution	1.68 Å
Binding residue (original residue number in PDB)	D98 D102
Binding residue (residue number reindexed from 1)	D98 D102
Annotation score	4

Enzymatic activity

Catalytic site (original residue number in PDB)	K48 H93 D98 D102 R107 D170 K207 F246 D250 D251
Catalytic site (residue number reindexed from 1)	K48 H93 D98 D102 R107 D170 K207 F246 D250 D251
Enzyme Commision number	?

Gene Ontology

	Molecular Function
GO:0004659	prenyltransferase activity
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups

	Biological Process
GO:0008299	isoprenoid biosynthetic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:6sdo, PDBe:6sdo, PDBj:6sdo
PDBsum	6sdo
PubMed
UniProt	Q8WS26

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