Structure of PDB 6s3i Chain A Binding Site BS01

Receptor Information
>6s3i Chain A (length=434) Species: 56957 (Thermus oshimai) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSSEQQRAFLAVTQTPHPAHLITGPAGTGKTTLLYALQEFYKGRAVTLAP
TGTAALQARGQTVHSFFRFPARLLRYRHPEDIRPPGPHSPLRKAIEQMEV
LILDEVGMVRVDLLEAMDWALRKTRKRLEEPFGGVKVLLLGDTRQLEPVV
PGGEEALYIARTWGGPFFFQAHVWEEVALRVHRLWESQRQREDPLFAELL
KRLRQGDPQALETLNRAAVRPDGGEEPGTLILTPRRKEADALNLKRLEAL
PGKPLEYQAQVKGEFAETDFPTEAALTLKKGAQVILLRNDPLGEYFNGDL
GWVEDLEAEALAVRLKRNGRRVVIRPFVWEKIVYTYDSEREEIKPQVVGT
FRQVPVRLAWALTVHKAQGLTLDKVHLELGRGLFAHGQLYVALTRVRRLQ
DLSLSRPIAPTELLWRPEVEVFETRIQEGIWQKS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6s3i Structural and functional studies of SF1B Pif1 from Thermus oshimai reveal dimerization-induced helicase inhibition.
Resolution2.455 Å
Binding residue
(original residue number in PDB)		P117 T118 G119 T129 H131 A138 V216 R302 R303 N356 N364 W396 H432 F451
Binding residue
(residue number reindexed from 1)		P50 T51 G52 T62 H64 A71 V149 R235 R236 N289 N297 W329 H365 F384
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003678 DNA helicase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000723 telomere maintenance
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:6s3i, PDBe:6s3i, PDBj:6s3i
PDBsum6s3i
PubMed33784404
UniProtK7RJ88

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