Structure of PDB 6s3h Chain A Binding Site BS01

Receptor Information
>6s3h Chain A (length=422) Species: 751945 (Thermus oshimai JL-2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLSSEQQRAFLAVTQTPHPAHLITGPAGTGKTTLLYALQEFYKGRAVTLA
PTGTAALQARGQTVHSFFRFPARLLRYRHPEDIRPPGPHSPLRKAIEQME
VLILDEVGMVRVDLLEAMDWALRKTRKRLEEPFGGVKVLLLGDTRQLEPV
VPGGEEALYIARTWGGPFFFQAHVWEEVALRVHRLWESQRQREDPLFAEL
LKRLRQGDPQALETLNRAAVRPDGGEEPGTLILTPRRKEADALNLKRLEA
LPGKPLEYQAQVKGEFAETDFPTEAALTLKKGAQVILLRNDPLGEYFNGD
LGWVEDLEAEALAVRLKRNGRRVVIRPFVWEKIVVVGTFRQVPVRLAWAL
TVHKAQGLTLDKVHLELGRGLFAHGQLYVALTRVRRLQDLSLSRPIAPTE
LLWRPEVEVFETRIQEGIWQKS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6s3h Structural and functional studies of SF1B Pif1 from Thermus oshimai reveal dimerization-induced helicase inhibition.
Resolution2.06 Å
Binding residue
(original residue number in PDB)		P117 T118 T129 H131 R135 A138 V216 P218 R302 R303 F332 P338 W396 E397 K398 T430 H432 K433 F451
Binding residue
(residue number reindexed from 1)		P51 T52 T63 H65 R69 A72 V150 P152 R236 R237 F266 P272 W330 E331 K332 T351 H353 K354 F372
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003678 DNA helicase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000723 telomere maintenance
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:6s3h, PDBe:6s3h, PDBj:6s3h
PDBsum6s3h
PubMed33784404
UniProtK7RJ88

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