Structure of PDB 6s22 Chain A Binding Site BS01

Receptor Information

>6s22 Chain A (length=529) Species: 59729 (Taeniopygia guttata) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HCLPGHYTPVELKPFLDRPLQDPNAPGASGKAFKTINLNSEEQKEKQAGE
EKHCFNAFASDRISLHRDLGPDTRPPECIEQKFKRCPPLPTTSIIIVFHN
EAWSTLLRTVHSVMYTSPAILLKEIILVDDASVDEYLHDKLDEYVKQFQI
VKVVRQKERKGLITARLLGASVATGETLTFLDAHCECFYGWLEPLLARIA
ENPVAVVSPDIASIDLNTFEFSKPSPYGHSHNRGNFDWSLSFGWESLPKH
ENKRRKDETYPIRTPTFAGGLFSISKDYFEYIGSYDEEMEIWGGENIEMS
FRVWQCGGQLEIMPCSVVGHVFRSGTQVITRNQVRLAEVWMDEYKEIFYR
RNTEAAKIVKQKTFGDISKRIDLRQRLQCKNFTWYLSNVYPEAYVPDLNP
LFSGYLKNIGNRMCLDVGENNHGGKPLIMYSCHGLGGNQYFEYSAHHEIR
HNIQKELCLHASKGPVQLRECTYKGQKTFAVGEEQWLHQKDQTLYNEALH
MCLTGNGEHPSLASCNPSDPFQKWIFGQN

Ligand information

>6s22 Chain F (length=12) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

NTPIPRRHTRSA

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6s22 Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3.
Resolution	1.96 Å
Binding residue (original residue number in PDB)	N325 S332 W337 W385 F415 R416 S417 T427 N521
Binding residue (residue number reindexed from 1)	N232 S239 W244 W292 F322 R323 S324 T326 N420

Enzymatic activity

Enzyme Commision number

2.4.1.41: polypeptide N-acetylgalactosaminyltransferase.

External links

PDB	RCSB:6s22, PDBe:6s22, PDBj:6s22
PDBsum	6s22
PubMed	31932717
UniProt	H0ZAB5\|GALT3_TAEGU Polypeptide N-acetylgalactosaminyltransferase 3 (Gene Name=GALNT3)

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